Mark A. Isaeff, MD
Internal Medicine

Get Started Today
About Mark A. Isaeff, MD
I believe that we all have different gifts and talents. For me, I have been given the gift of teaching and healing. I have an innate sense for identifying problems and illness in people and communicating them in understandable ways. Looking each person in the eye I give you my undivided attention. You are exceedingly valuable and infinite in worth. I will not judge you. As your doctor, I am your friend. And as your friend, I will share my gifts with you. In the end healing is easier when relationships are found.
San Antonio, TX
Internal Medicine 1999-2001
Chief Resident, Internal Medicine 2001-2002
Excellence in Internal Medicine
Excellence in Outpatient Care
San Antonio, TX
Internal Medicine 1998-1999
Washington, DC
Doctorate of Medicine with Distinction 1998
Oscar Benwood Hunter Award
DF Kane, AF King, SM Dodek Award
Huron W. Larson Award
Pathology Honor Society Award
Berkeley, CA
Bachelor of Science, Molecular Cell Biology 1992
Benefits of joining Dr. Isaeff's practice with MDVIP
The office of Mark A. Isaeff, MD
Mon | 8:30 AM - 5:00 PM |
Tue | 8:30 AM - 5:00 PM |
Wed | 8:30 AM - 3:00 PM |
Thu | 8:30 AM - 5:00 PM |
Fri | 8:30 AM - 12:00 PM |
Sat | Closed |
Sun | Closed |

Reviews from the web








Dr. Isaeff has always treated me with utmost respect and care. He has spent a lot of time listening to my concerns and educating me on medical advice specific to my needs based on my bloodwork and medical history, such as nutrition and weight loss.
He obviously stays on top of the latest medical information by reading, studying medical journals, and attending workshops/conferences. He shares up to date information with me that he thinks might apply to me.
Any time he has sent me to a specialist for broken foot, colonoscopy, etc, it is obvious the other professionals hold him in professional esteem by the kind remarks they’ve made. (Each one he’s sent me to have also been top doctors in their field, as well.) His staff have arranged the referrals and set up timely appointments for me. He has followed up with those specialists and checked on me, sharing and interpreting results with me making sure I understand and feel satisfied.
The staff of Dr. Isaeff are also fantastic! The people who work for and with him are extremely professional, yet friendly and personable. Each one has always greeted me by name and gives me more respect and attention than I’ve ever received in a medical office. They, as well as the doctor himself, make me feel as if I am their only patient and their personal friend. I know they are very busy and yet they take time to make me feel special! I’m sure they do this with all of their patients, this is very rare!
I drive 150 miles one way to see Dr.Isaeff because I have moved and just will not even try to find a replacement dr. Any time I call or text the office or even the doctor personally, the response is practically immediate with an apology for not responding faster! This is so uncommon! I truly appreciate the care I get from Dr. Isaeff as well as his staff.





What a wonderful doctor we have in San Antonio, his staff are extremely helpful and fun to visit with. Mark really listens to me and he has a gentle way of helping me understand how to take better care of myself. I would recommend him to friends and family.


Frequently Asked Questions
Doctors who operate in the MDVIP models typically see far fewer patients than traditional primary care doctors. That gives them more time to develop deeper doctor-patient relationships that can lead to better outcomes. They can also offer conveniences that most primary care doctors can’t, including same- and next-day appointments. They’re available after hours for urgent matters. And they have time to focus on prevention. That focus begins with the MDVIP Wellness Program, which patients pay for with their annual membership fee.
Most MDVIP-affiliated primary care practices accept insurance (your physician can tell you whether they accept your specific insurance plan). Your annual fee pays for preventive care medical services that insurance usually doesn’t cover (e.g., advanced diagnostic testing and screenings). Your MDVIP-affiliated physician will continue to bill your insurance and charge copays, co-insurances and deductibles as he or she currently does for other medical services like sick visits.
MDVIP makes wellness and prevention easier by providing your physician with innovative tools and technology. MDVIP supports your physician’s practice and seeks to eliminate barriers to a positive healthcare experience. Your doctor will determine whether and how to incorporate these tools at his/her discretion.
**The message above is a personal introduction from the physician, intended to help you get to know them better. The views, opinions, and statements expressed above are solely those of the physician and do not necessarily reflect the views or positions of MDVIP. This content is intended for general background purposes only and does not constitute medical advice, diagnosis, or treatment. Any mentions of expertise or quality of care are personal expressions and should not be interpreted as guarantees of performance or outcomes.