Ivan N. Mefford, MD, PhD

My Philosophy and Approach to Wellness...

Going to the doctor should not be intimidating or anxiety provoking.  When you come to my office, I want your visit to be met with comfort, caring, warmth and humor -- coordinated with professional and informed attention to your medical problems.  Your health is your most important possession.  A partnership built on trust and collaboration makes it possible for us to manage your most important asset together.

Physician Profile


Kentucky State University
Frankfort, KY
Bachelor of Science, Chemistry 1974
University of Kansas
Lawrence, KS
Doctor of Philosophy, Analytical Chemistry 1978
Medical School
Duke University School of Medicine
Durham, NC
Doctorate of Medicine 1995
University of Texas, Memorial Family Practice
Houston, TX
University of Texas, Memorial Family Practice
Houston, TX
Family Practice 1995-1998
Chief Resident 1997-1998



Professional Society Memberships

American Medical Association

Professional Affiliations and Appointments

Supervisor, Texas Higher Education Coordination Board Family Practice Residency Program, Rural Rotation 2006-present
Chief of Staff, OakBend Medical Center 2004

Hospital Affiliations

OakBend Medical Center
Memorial Hermann Sugar Land Hospital
Methodist Sugar Land Hospital

Honors and Awards

America's Top Family Doctors, Consumers Research Council of America 2003-2012
Beta Kappa Chi, Scientific Honor Society
Presidential Citation: National Association for Equal Opportunity in Higher Education 1987

Published Works

Mefford, I.N., Kincl, L., Dykstra, K.H., Simpson, J.T., Markey, S.P., Dietz, S. and Wightman, R.M., Facile Oxidative Decarboxylation of 3,4-dihydroxyphenylacetic Acid Catalyzed by Copper and Manganese Ions, Biochimica et Biophysica Acta, 1290,224-230, 199
Burnet, P.W., Mefford, I.N., Smith, C.C., Gold, P.W. and Steinberg, E.M., Hippocampal 5-HT1A Receptor Binding Site Densities, 5-HT1A Receptor Messenger Ribonucleic Acid Abundance and Serotonin Levels Parallel the Activity of the Hypothalamic-Pituitary-Adr
Mefford, I.N. and Wade, E.U., Proton pump inhibitors as a treatment method for type II diabetes, Medical Hypotheses, 73, 29-32, 2009.
Mefford. I., Crouch, M.A. and Wade, E., Effect of concomitant proton pump inhibitor therapy on type 2 diabetes control, Family Medicine, 42 (suppl 2), 2010
Crouch, M.A., Mefford, I.N. and Wade, E.U., Proton pump inhibitor therapy associated with lower glycosylated hemoglobin levels in type 2 diabetes, J Am Board Fam Med, 25, 50-54, 2012
Mefford, I.N., Mefford, J.T. and Burris, C.A., Improved diabetes control and pancreatic function in a type 2 diabetic after omeprazole administration, Case Reports in Endocrinology, Volume 2012, Article ID 468609, 2012


Research, Clinical Trials (Especially related to Diabetes), Primary Investigator for 5 Clinical Trials since 2008, Gardening, Cattle (Owner of Mefford Family Farms with Belgian Blue Cows in Kentucky) and College Basketball

Patient Testimonials

  • Member: Tracy

    Best Doc and staff ever...almost make sick being fun!

  • Member: Louis

    Having an M.D. who is willing and capable of coordinating with multiple specialists is so important in my husband's life. As a st...

  • Member: Steve

    I've been driving approximately 80 miles round trip to see Dr. Mefford for the past 12 years or so when I could've settled for a d...

  • Member: Laura & Nahum

    As new members, our experience with Dr. Mefford is limited, however in the short time we've been with him all of our contacts have...