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Dr. Alyssa M. Degnan

Internal Medicine

Hospital Affiliations
Aiken Regional Medical Center
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Dr. Alyssa M. Degnan

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MDVIP Annual Membership Fee
MDVIP’s annual fee covers the Wellness Program and generally can be made in quarterly, semi-annual and annual payments. Payment options vary by physician.
Quarterly
$687.50*
Semi-Annual
$1,375.00*
Annual
$2,750.00*
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About Dr. Alyssa M. Degnan

"Wherever the art of medicine is loved, there is also a love of humanity." Hippocrates
 
My goal as your private doctor is to provide you with highly personalized healthcare that will effectively treat your current health problems and help to prevent new ones from developing. Practicing good medicine includes a partnership between doctor and patient – a partnership based on mutual trust and respect that is earned, not given. In my MDVIP-affiliated practice, you will be treated as if you are a member of my family in a warm and welcoming atmosphere, and I will work with you at each step to assist you with making informed decisions toward achieving your goals. Whether it’s running your first marathon, reducing the use of medication or improving your nutrition, we will work together as a team to help make a happy, healthy future your reality. There are no shortcuts to being healthy, no simple formulas and no "one size fits all" approach when it comes to the well-being of my patients as each of you are wonderfully unique individuals!
 
With over 17 years of experience practicing in the community, I have relationships with many specialists in the Central Savannah River Area to help with your unique needs and I am affiliated with Aiken Regional Medical Centers. My primary care office is located in Aiken, South Carolina. I am passionate about fitness, exercise and tennis and would welcome the opportunity to exercise with my patients as we reach our health care goals together.

Residency

Pennsylvania Hospital, University of Pennsylvania
Philadelphia, PA
Internal Medicine 1999-2001
Chief Resident 2001-2002

Internship

Frankford Hospital
Philadelphia, PA
1998-1999

Medical School

Lake Erie College of Osteopathic Medicine
Erie, PA
Doctor of Osteopathic Medicine 1998

Undergraduate

The College of New Jersey
Hillwood Lakes, NJ
Bachelor of Science, Biology and Chemistry 1993
Magna Cum Laude

American Board of Internal Medicine
Advanced Cardiac Life Support
Basic Life Support

Aiken Regional Medical Center

Medical Director, Home Health Services 2010-present
Hospice Medical Director, Kindred Home Health 2017-present
Supervising Physician for Nurse Practitioner, Hope Health Inc. 2017-present

1st Place in Internal Medicine, Top Docs 2024, Aiken Standard
Best of Aiken Physician Award 2017
Most Compassionate Doctor, Patient's Choice Award 2010

American College of Physicians
American Osteopathic Association
South Carolina Medical Association

South Carolina

Coaching youth basketball, tennis, ultimate fitness challenge and travel

Benefits of joining Dr. Degnan's practice with MDVIP

MDVIP Wellness Program
Expect comprehensive screenings and tests and a custom wellness plan designed for you.
Better Doctor-Patient Relationship
97% of MDVIP members are satisfied with their relationship (vs 58% in traditional PCP).
Same/Next-Day Appointments
See Dr. Degnan quickly and take your time during each appointment.
Reachable 24/7
Reach Dr. Degnan by phone after-hours and on weekends.
Smaller Practice Size
MDVIP practices are smaller than most primary care practices, which means your doctor has more time to help you.
Your Dedicated Doctor
See Dr. Degnan when you go to the office — not someone else like a nurse practitioner or physician assistant
Travel Benefits
If you need urgent care while traveling, your physician can help arrange your care with a local hospital, pharmacy or doctor.
Medical Centers of Excellence
For patients who need care beyond what is available locally, MDVIP can connect your doctor with specialists at some of the country’s leading medical institutions
Better Health Outcomes
Members have better control of chronic conditions like type 2 diabetes, high cholesterol and hypertension.

The office of Dr. Alyssa M. Degnan

Primary Office
3000 Woodside Executive Ct.
Aiken, SC 29803
Get Directions
Hours
Mon 8:00 AM - 5:00 PM
Tue 8:00 AM - 5:00 PM
Wed 8:00 AM - 5:00 PM
Thu 8:00 AM - 5:00 PM
Fri Closed
Sat Closed
Sun Closed

What our members are saying

When my husband passed away three years ago, I was in such deep grief that my thoughts turned dark and my world felt overwhelming. I had a check up with Dr. Degnan and at some point I started getting teary eyed. Dr. Degnan sat and talked with me for almost an hour. She wanted to hear all about my life with Bob and I felt her concern was sincere and thoughtful. Never have I had a doctor spend…
January 17, 2026
Dr Degnan is a great personal physician. She takes time to explain in clear terms any and all questions I have as a patient. Her empathy and compassion are second to none. She has great insight and willing shares everything you need to know about your health. I am very fortunate to have her as my primary care physician.
January 16, 2026
Dr. Degnan the work you do is important and very much appreciated. Sending a little heartfelt appreciation your way today. Just want to express my deep gratitude for the work you do day after day for your patients. For all you do and for the kind, thoughtful and caring way you do it, whether it's through medicine or just human kindness, is a blessing to all of your patients. I am truly blessed…
January 29, 2025
I moved to Aiken in 2008. After getting settled, one of my first things was to find a new doctor. I had a doctor who was very good in my previous location so I knew I wanted one equally as good. Talked to several people and the name Alyssa Degnan was mentioned by more than one person. But, they added they didn’t think she was taking new patients. I decided I would call her office anyway and…
January 28, 2025

Reviews from the web

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03/19/2026 Brenda Proctor
I have had wonderful experiences with her, would refer her to anyone.❤️
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03/18/2026 Almond Allison
I have been blessed to have My Wonderful, caring doctor for 20 years. From day one until this present time she’s always been magnificent in the way she cares for her patience’s. I would recommend her to everyone that is looking for the Kind of care that she gives.
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03/16/2026 H Bryant
Very professional and knowledgeable of her profession. Case load is smaller making it much easier to get in for appointments.
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03/09/2026 wendell haight
In 2025 I had major surgery and then experienced complications when I got home. Dr. Degnan's office responded immediately and saved my life. I am forever grateful to Dr. Degnan and her staff.
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04/21/2025 valerie burrus
Yeah if you have $2,000 a year above your annual insurance
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02/05/2025 Hugh Hanlin
In 2015 I retired from my position of 35 years as a Professor of Biology. That same year my best friend Chuck from graduate school moved to Aiken so that we could share our retirement years together. One of the first things he asked of me was the name of my personal physician. He was shocked when I responded that I had none! He then asked when I had last had a complete physical exam. When I responded that the closest thing I had ever had to a physical exam was the one that was performed when I was drafted into the army in 1972, he shamed me! What can I say? I have always been a bit stubborn and contrary to ordinary, not hesitant to push boundaries.

When I inquired from my former students and friends in the health care fields who they would recommend as a personal physician, the overwhelming recommendation was Dr. Alyssa Degnan. Even after our first visits with her, both Chuck and I were impressed that she was so personable and empathetic while also instilling confidence in her expertise, thoroughness, and professionalism. I also found her nursing and support staff to be equally friendly and competent. When I informed Dr. Degnan that I had never had a personal physician and that it had been over 40 years since I had ever had a physical exam, she responded, “Well, it looks like we have a lot of work to do!” And so, the journey began.

The results of my first exam showed that my PSA levels were off the charts (50+). I could see the concern in her eyes, and she immediately referred me to a relatively new urologist in Aiken. He was exceptional (as every physician to whom I have been referred by Dr. Degnan has been). Unsurprisingly, when he biopsied my prostate every sample contained cancer cells, and a scheduled cryotherapy followed. I have had routine follow-ups since that time, and my PSAs have stabilized at an acceptable level.

What followed was a series of referrals for tests (eg. pelvic MRI, abdominal aorta ultrasound, abdominal/pelvic CT, liver/hepatic ultrasound, etc.). Following a bout with peptic ulcers, I received an endoscopy and colonoscopy. After these, she continued to manage my physical health with appropriate medications. She was committed to seeing that I had the care I had missed for so many years.

In 2019 we lost Chuck to esophageal cancer. I had transported him to all of his appointments including his chemotherapy treatments and extended trips to the Mayo clinic in Florida, and I was there in his last moments to help him die. It left me emotionally fragile. In 2020 I learned that my youngest son had been diagnosed with Burkitt's lymphoma, an aggressive blood cancer, and ten days later that my oldest son had committed suicide. I was a “basket case,” but I was blessed to have Alyssa there to provide a shoulder to cry on, a loving presence for advice on how to face my issues, and to prescribe medication for depression when I chose to continue to see her rather that being referred elsewhere for counseling. Today I am able to laugh again and face each morning with a good outlook.

I love Alyssa Degnan, and I know that she loves me. I know that she has saved my life and given me hope for that life to continue. She is no longer just my personal physician but also a dear friend.
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03/29/2024 Beverly Zanotti
Very pleased with the attention I have received.
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02/21/2024 Lynda Platt
I was fortunate to be a patient of Dr. Alyssa Degnan’s over 20 years ago when I first relocated to this area. After receiving a diagnosis of Type 2 diabetes, Dr. Degnan and her staff were extremely supportive as I navigated my way through the learning curve of living with and controlling this disease. Eight years ago I moved out of state, but went with the assurance that she was still available to me if needed. Fast forward eight years and I am once again under her care and delighted with the practice and outstanding office staff. She is a compassionate, skillful and thorough physician whose concern for her patients is obvious with each visit. I am so comforted in once again calling her ‘my’ doctor.
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02/20/2024 Rick Catts
I wanted to thank Dr Degnan and her staff for creating a friendly easy environment. I highly recommend their office Thanks Rick
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02/20/2024 tom weyl
Dr. Degnan is knowledgeable and very helpful. She's takes the time to explain my medical condition and what is needed.
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02/16/2024 Add
I love having an MDVIP doctor when I travel and I highly recommend concierge level service when you actually receive it. Unfortunately, healthcare has deteriorated, in my opinion, after Covid everywhere- including at this office. Customer service is no longer what I had come to expect. Hence, I have changed doctors to another MDVIP doctor.
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12/03/2023 Barry Olliff
Dr Degnan is what you might call an old fashioned doctor. She has time and looks at patients well being holistically. Time is something that most patients don’t spend with their doctor. Via MD VIP and Dr Degnan it’s possible to get into preventative medical treatment at a reasonable price.
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03/16/2023 Doris Briggs
Dr. Degnan is readily available. Her staff of the nursing and secretarial are very professional and friendly. I feel like I am in good hands all around.
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03/03/2023 Robert Low
Dr. Degnan's attention to detail regarding my health issues is superior to any other physician I have previously seen. She and her staff are proactive and her explanations of my conditions are easy to understand. Her bedside manner makes me feel very comfortable in her office.
Dr.Degnan is the best physician I've ever been associated with. Most grateful that she is my doctor.
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01/17/2023 Paula Brown
Appointments always kept on time. Very prompt. Enjoy the specialized attention to my medical condition.
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12/14/2022 John Malmborg
Great care from people who really take an interest in your health.
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11/21/2022 Steven Coward
Simply the best internist ever! Her exceptional knowledge supports effective analytics and she shares her knowledge in an inclusive manner that gives you the confidence you are in the right hands.
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11/18/2022 Carol Wilmot
No waiting. Professional staff and very friendly. Saw doctor with a few minutes.
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11/03/2022 RM Lyons
My husband and I have been patients of Dr. Degnan since 2008. She is knowledgeable, caring and spends time explaining details like no other doctor we have ever been to. If we have a problem that needs a specialist, she sends us to the best in the area. We love her and the staff like family. We will be with her to the end!
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09/28/2022 Connie Henrich
Dr. Degnan is the doctor I would liked to have found 30 years ago! Personable, professional, pro-active, very thorough; just the best. She gives excellent referrals, is a great diagnostician and literally saved my life by helping to diagnose my multiple myeloma and referring me to an excellent hemotologist/oncologist.
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09/08/2022 John
Five stars are not enough! Dr. Degnan is the creme de la creme of doctors. Beyond the excellent care she personally provides, she (and her staff) become active advocates to make sure you don't have to face the health care maze by yourself. When you are seeing a specialist of in a hospital It's a real comfort to know that your primary care doctor (who knows you best) has your back. .
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09/02/2022 Rita Marshall
Dr. Degnan is easy to talk with, professional, kind and very helpful.
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08/02/2022 Lydia Kleiman
It is a pleasant experience visiting with Dr. Degnan. She always puts me at ease and readily shares solutions to my questions. I am in awe of her vast knowledge in the medical field. She is very nice and has a wonderful personality. I am never nervous to make an appointment because I know I will be well taken care of.
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08/02/2022 helen naylor
This is a brilliant doctor and a kind and helpful staff. I have been a patient more than 15 years and I believe my health care is what keeps me grounded. I am thankful the team knows me as well as they do. Helen Naylor
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03/16/2022 Dorothy Ridley
Dr. Degnan is thorough, efficient, compassionate and an excellent physician. Everyone should be able to have someone of her qualifications to help them manage their healthcare.
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03/08/2022 Elizabeth Blackwell
Dr. Degnan and her staff are wonderful! They are professional, attentive and caring. I am a new patient and already feel that I am going to see a friend when I go to the doctor.
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02/24/2022 Janet Thompson
I have always passed on good information to my retired ftiends about Dr Degnan and MDVIP. Dr Degnan and staff are wonderful. Im so appreciative.
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02/17/2022 Jan Barker
Dr. Degnan is one in 1 million! She is readily available as is her office staff. She listens with empathy and understanding and always seems to come up with a plan of action and the resources to achieve it. Her office is peaceful and inviting and one never feels rushed by her or her staff. She has patiently guided me through both physical and emotional issues. Can’t imagine going anywhere else…
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02/16/2022 Cheryl Stanek
The only complaint I have is your billing method. I would like to have a heads up that you are going to charge my credit card instead of just charging in. Perhaps I’d like to use a different card or just know in advance that the charge is coming.
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02/16/2022 Margaret Mossbarger
Dr. Degnan is professional, friendly, down-to-earth, practical, and a darn good doctor. Glad to have her as my physician.
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02/16/2022 Judy Mittino
Dr. Degan is an extraordinary doctor. She is compassionate, involved with her patients and extremely knowledgeable. She also goes the extra mile to assure her patients get the best care.
Her office staff is also exemplary.
My husband and I are so glad we selected Dr. Degan to be our primary physician.
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02/16/2022 Todd Johnson
excellent physician who spends a great deal of time with her patients with wonderful bedside manner and very helpful staff.
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01/28/2022 Jim Ruthven
Dr. Degnan Is an excellent physician, very thorough and very personable. Highly recommended!
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12/21/2021 Cynthia Catts
I've never had a more pleasant experience at a doctor's office. Dr. Degnan and her entire staff are the epitome of kindness and professionalism.
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12/20/2021 Linda Walters
Dr. Degnan is a wonderful doctor. She is so smart. I feel so lucky to have her as my doctor. She is very responsive to my needs. She has a great staff who are very helpful. She took excellent care of me during a heart issue had had last year. I would highly recommend Dr. Degnan to be your doctor.
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12/14/2021 Ted Tronosky
I had another outstanding visit with Dr. Degnan today to review the results of my Annual Physical. My results were very good and I attribute my healthy condition to the care of Dr. Degnan and her staff. I feel blessed having Dr. Degnan as my Primary Care Doctor.
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11/29/2021 Annie Allison
My experience with this office has been nothing less than extremely wonderful and satisfying. The physician and staff are always caring,professional, respectful and very attentive to their patients. Wouldn't trade them for anything or other any other practice.😊😊😊
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10/21/2021 Liller Hamilton
Thanks for the info. My husband and I plan to take a three day vacation in the mountions of NC.

Frequently Asked Questions

Doctors who operate in the MDVIP models typically see far fewer patients than traditional primary care doctors. That gives them more time to develop deeper doctor-patient relationships that can lead to better outcomes. They can also offer conveniences that most primary care doctors can’t, including same- and next-day appointments. They’re available after hours for urgent matters. And they have time to focus on prevention. That focus begins with the MDVIP Wellness Program, which patients pay for with their annual membership fee.

Most MDVIP-affiliated primary care practices accept insurance (your physician can tell you whether they accept your specific insurance plan). Your annual fee pays for preventive care medical services that insurance usually doesn’t cover (e.g., advanced diagnostic testing and screenings). Your MDVIP-affiliated physician will continue to bill your insurance and charge copays, co-insurances and deductibles as he or she currently does for other medical services like sick visits.

MDVIP makes wellness and prevention easier by providing your physician with innovative tools and technology. MDVIP supports your physician’s practice and seeks to eliminate barriers to a positive healthcare experience. Your doctor will determine whether and how to incorporate these tools at his/her discretion.

**The message above is a personal introduction from the physician, intended to help you get to know them better. The views, opinions, and statements expressed above are solely those of the physician and do not necessarily reflect the views or positions of MDVIP. This content is intended for general background purposes only and does not constitute medical advice, diagnosis, or treatment. Any mentions of expertise or quality of care are personal expressions and should not be interpreted as guarantees of performance or outcomes.